Efficient Modeling of Nanoparticle Transport in Human Airway

From Montana Tech High Performance Computing

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Tianyu Zhang

Department of Mathematical Science, Montana State University

There exists a great need to model nanoparticle transport and deposition in the human airways for therapeutic and health reasons. The recent explosion of interest in the health impacts of nanoparticles and the use of nanoparticles as a platform for drug delivery has pushed many researches to seek new approaches for accurately predicting nanoparticle deposition patterns in a patient specific manner early in the development of a new therapy. The Finite Element Method (FEM) is a popular approach used by many researchers for modeling nanoparticle transport in the human airways. HPC was used to extend the stabilized FEM for modeling nanoparticle transport in the human airways developed and evaluated in a previous project for nanoparticles from 1 nm to 150 nm to the hp-FEM context and gather some preliminary data.